| Author | Message | ||
     sunnyblue |
My sister had one of her children tested for long qt. It was positive for type 1. She has had the other two kids tested to look for type 1. One child the doctor thought absolutely did NOT have qt shows to have it, and the other that he thought did have it... shows she did not. The question has been posed and to the lab if it were possible for one family to have more then one kind of qt. My sister tested positive for type one also. Her husband was negative and his qt is quite low on the ekg. | ||
| Dr. Jorgen Kanters Username: Jorgen Registered: 08-2003 |
The chance to have LQTS is 1:5000. that means that having 2 kinds of LQTS in the family must be 1: (5000*5000) = 1: 25.000.000 The chance is very low but can not be overruled. I would say its more probable that the one kid with normal QT and the mutation is a silent carrier of LQTS (which are 10% of all LQTS patients.) The other kid without the mutation and QT prolongation could just be a normal variant with borderline QT which constitutes 2.5 % of all healthy sujects. If the QT prolongation is longer than 0.47 one have to evaluate the case carefully. | ||
| Kimmy99 Username: Kimmy99 Registered: 11-2006 |
I have recently received ressults from genetic testing and have mutations in KCNQ1,SCN5A and KCNE1 leading me to believe I have LQT1 LQT3 and LQT5. My parents and sister have just had their blood drawn for testing. A EKG was taken at the time of the blood draws and my parents didn't show anything, however my sister's EKG showed a prolonged qt at 493. The doctor wants to wait for the results of my sisters testing before starting her on any medication (she has no symtoms) and he said that she could not have the same types as I have. Is this possible. |